List of platinum based chemotherapy agents

Web20 mei 2008 · 19088 Background: Single-agent chemotherapy as a first-line treatment is currently considered as the standard approach for elderly patients with advanced NSCLC. Since the platinum-based combination chemotherapy is the standard treatment for younger patients with advanced NSCLC, it may also have more effective for elderly. We … WebL01XA — Platinum compounds. Drugs. Drug. Drug Description. Cisplatin. A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. Nedaplatin. Used in the treatment of non-small cell lung cancer, small cell lung cancer, oesophygeal cancer, and head and neck cancers . Oxaliplatin.

Frontiers Platinum-Based Neoadjuvant Chemotherapy Before …

Web8 nov. 2024 · Among the 2415 TNBC patients who underwent platinum-based neoadjuvant chemotherapy, this study showed statistically significant improvement in pCR rates compared to non-platinum-based treatment. However, this data is affected by moderate heterogeneity among the studies, which has been associated with the varied agents … Web2 dagen geleden · Patients who completed and responded to first-line platinum-based chemotherapy with carboplatin or cisplatin were randomly assigned to receive oral senaparib at a starting dose of 100 mg, or ... northern bushcraft book https://kmsexportsindia.com

Nanoparticle-Based Combination Therapy for Ovarian Cancer

Web1 mei 2024 · Platinum complex drugs commonly used in chemotherapy as anticancer agents. Pt chemotherapeutics make up roughly 50% of all chemotherapeutic drug regimens. Platinum drugs are used in both Pt (II) and Pt (IV) oxidation states. Pt antitumor complexes have at least three components in common: Web1 apr. 2024 · Platinum-based chemotherapy regimens have been proven to be effective in various cancers; however, considerable toxicities may develop and can even lead to treatment discontinuation. Diverse factors may influence adverse treatment events, with pharmacogenetic variations being one prime example. Polymorphisms within the … WebAlkylating agents are effective during every phase of the life cycle of a cancer cell, which means they are effective for treating a wide range of cancers. They are most effective for treating slow-growing cancers such as leukemia and solid tumors , but are also used in the treatment of breast, lung, ovarian, and prostate cancers; lymphomas, myelomas, and … how to rig a minifish sailboat

Risk of Leukemia after Platinum-Based Chemotherapy for Ovarian Cancer

Category:Pharmacogenomics of platinum-based chemotherapy in NSCLC

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List of platinum based chemotherapy agents

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Web4 apr. 2024 · Oxaliplatin (brand name: Eloxatin) is a platinum-based chemotherapy drug that works by disrupting DNA activity in the cancer cells to lead to cell toxicity and death. It is classified as an "alkylating agent". Oxaliplatin is given into a vein. It's used together with fluorouracil and leucovorin to treat more advanced colon and rectal cancer. WebThe trial demonstrated statistically significant improvements in OS and PFS for patients receiving cemiplimab-rwlc compared to those treated with platinum-based chemotherapy.

List of platinum based chemotherapy agents

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This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), … Meer weergeven • Altretamine • Bendamustine • Busulfan • Carboquone • Carmustine Meer weergeven • Ixabepilone Meer weergeven • Vorinostat • Romidepsin Meer weergeven • Etoposide • Teniposide • Tafluposide Meer weergeven Aclarubicin • Daunorubicin • Doxorubicin • Epirubicin Meer weergeven • Abraxane • Cabazitaxel • Docetaxel • Larotaxel Meer weergeven • Belotecan • Camptothecin • Exatecan • Gimatecan • Irinotecan • Topotecan Meer weergeven Web5 okt. 2024 · Out of 42 patients diagnosed with advanced non-resectable NSCLC who were treated with platinum-based chemotherapy or had symptoms treated, we extracted 42 cases with complete follow up. This included 17 individuals who received symptoms treatment only (natural history, NH, cohort) and 25 patients who underwent platinum …

WebThe chemo drugs may be given on one or more days in each cycle. Chemo drugs used to treat endometrial cancer may include: Paclitaxel (Taxol ®) Carboplatin. Doxorubicin (Adriamycin ®) or liposomal doxorubicin (Doxil ®) Cisplatin. Docetaxel (Taxotere ®) Most often, 2 or more drugs are combined for treatment. Web1 jun. 2016 · This list of chemotherapeutic agents covers the cancers each drug is used for, as well as the recommended dosage and possible toxicities of the therapy. ... Non–small-cell lung cancer with progression on or after a platinum-based chemotherapy. Dosage: 3 mg/kg every 2 weeks.

Web21 sep. 2016 · Randomized phase II and III clinical trials comparing first-line palliative platinum-based chemotherapy with the same regimen without platinum or with platinum replaced by a nonplatinum agent were identified by electronic searches of Medline, Embase, and Cancerlit, and hand searches of relevant abstract books and reference lists. WebSingle new agents reportedly produce promising response and survival effects, but platinum-based doublets remain the standard chemotherapy for advanced non-small-cell lung cancer (NSCLC). The aim of this study was to evaluate the effectiveness of platinum for advanced NSCLC by carrying out a meta-analysis of trials that compared platinum …

Web14 apr. 2024 · Among 485 patients treated with first-line platinum-based chemotherapy, the probability of initiating maintenance avelumab increased over time following approval …

Web12 sep. 2024 · Each of the platinum coordination complexes is described separately with specific references. General references to their pharmacology and hepatotoxicity are given after this introductory … how to rig a minnow seineWeb22 apr. 2024 · that they might be more sensitive to platinum damage. Based on this biological rationale, several studies have evaluated the impact of adding platinum-based agents to standard chemotherapy; however, the results are con-flicting.8–10 Meanwhile, current recommenda-tions in several international breast cancer guidelines are also … northern business products catalogWeb28 okt. 2024 · Despite significant progress in drug development for advanced prostate cancer patients in the past decade, new active compounds, ideally for molecularly selected patients, are urgently needed. 1,2 Platinum-based compounds have been evaluated in clinical trials and used clinically as monotherapy or in combination with other … northern business products office suppliesWeb16 mrt. 2024 · We read with great interest the letter by Poggio et al.,1 updating their previous meta-analysis on the role of platinum compounds in neoadjuvant chemotherapy (NAC) of triple-negative breast cancer (TNBC).2 The current results indicate that adding a platinum agent significantly increases event-free survival (EFS) but not overall survival … northern business products duluth minnesotaWebPlatinum agents are used to treat lymphomas, sarcomas, breast, colorectal, germ cell, ovarian, lung, gastro-oesophageal and bladder cancers. Most retrospective data … how to rig an anchorWebOxaliplatin is platinum-based antineoplastic agent which has shown antitumor activity in a wide range of murine and human tumor cell lines in preclinical studies (Di Francesco et al., 2002). It has been approved for use in combination with 5-fluorouracil (5-FU) and folinic acid (FOLFOX regimen) for the therapy of advanced colorectal carcinoma ( Tesniere et al., … how to rig a mojo rigWebA list of chemotherapy drugs used to treat cancer. Click the drug name to learn how it works and common side effects. Skip Navigation. We value your privacy. Your user session will expire in 2 minutes. To stay logged in, please refresh the … northern bush katydid