Pin1 induction
WebDec 28, 2012 · In terms of Pin1-induced fat accumulation, it was revealed that the expression levels of peroxisome proliferator-activated receptor α and its target genes were higher in the livers of Pin1 KO mice than in controls. WebJun 10, 2013 · Induction of VEGF but not MMP2 and MMP9 by Pin1 To better understand the mechanisms of Pin1 on VSMC migration in T2D condition and to reveal downstream events of STAT3 signalling that were involved in the regulation of cell migration, we examined the expression of various migration regulatory proteins by Western blot analysis …
Pin1 induction
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WebJun 21, 2012 · Auxin concentrations high enough to trigger PIN1 convergent polarization and subsequent organ induction, therefore, can only appear at a certain distance from preexisting primordia (Reinhardt et al., 2003; Jönsson et al., 2006; Smith et al., 2006a). Hence, the interplay between auxin and its efflux transporter PIN1 provides a plausible ... WebPin1 expression was found to be up-regulated upon the induction of induced pluripotent stem (iPS) cells, and the forced expression of Pin1 with defined reprogramming factors …
WebOct 15, 2005 · The PIN1 expression pattern is somewhat variable, but under our experimental conditions PIN1 could be found predominantly at the basal (lower) side of stele and endodermis cells with occasional weak expression in the quiescent centre and up to the four youngest epidermis and cortex daughter cells ( Friml et al., 2002a ) ( Fig. 2D ). WebMar 13, 2013 · These results suggest that Pin1 is important for cardiac development and plays a role in the regulation of cardiac signal transduction after hypertrophic and mechanical stress because perivascular regions are hot spots for strain, remodeling, and increased cardioactive signaling in the heart.
WebApr 4, 2011 · National Center for Biotechnology Information WebJun 10, 2013 · Induction of VEGF but not MMP2 and MMP9 by Pin1 To better understand the mechanisms of Pin1 on VSMC migration in T2D condition and to reveal downstream events of STAT3 signalling that were involved in the regulation of cell migration, we examined the expression of various migration regulatory proteins by Western blot analysis …
WebJun 1, 2014 · Herein, we hypothesised that hepatic induction of Pin1 is a crucial factor for liver fibrogenesis and HSC activation. In fact, Pin1 inhibition by juglone treatments …
WebSep 14, 2009 · No induction of epithelial–mesenchymal transition (EMT) in Pin1-overexpressed MCF-7 cells. (a) Effect of Pin1 overexpression on the EMT phenotypes in MCF-7 cells. Representative immunoblots show E-cadherin, N-cadherin, and vimentin protein levels in both GFP-MCF-7 (control) and Pin1-MCF-7 cells serum-deprived for 18 h. mn river valley girl scoutsWebJul 29, 2024 · The initiation and induction of root primordia are of great importance for adventitious root (AR) formation in cutting propagation of horticultural and forestry crops. However, the underlying mechanisms orchestrating these early phases of AR formation remain largely unexplored. Here, we investigated the physiological and transcriptomic … mn rn online renewalWebFeb 4, 2024 · Compared with the control group, a significant induction of Pin1 expression and Pin1’s substrates cyclin D1 were observed after 0–9 h of incubation (Fig. 4a). in it what is ciaWebDec 2, 2008 · Here we describe a subcellular relocalization of PIN1, an auxin transport protein, in a single protoxylem cell in response to gravitropic curvature. This relocalization … mnr newsWebJul 10, 2013 · Pin1 overexpression has been frequently observed in several types of cancer tissues and has been shown to be a common and specific event in human cancers [13]. … initwidthWebAug 21, 2024 · A multitude of studies have demonstrated that PIN1 plays a paramount role in inflammation and endothelial dysfunction. [ 8, 14, 20 – 23] For example, Jeong et al have proved that PIN1 could induct and stimulate the expression of proinflammatory protein during rheumatoid arthritis progress. [ 4] in it what does api stand forWebMay 30, 2024 · Although Pin1 is a key drug target for treating acute promyelocytic leukemia (APL) caused by a fusion oncogene, much less is known about the role of Pin1 in other heterogeneous leukemia. ... Kondo A, Nagashima Y, Kimura H, Perrem K, Shigeri Y, Toyoda M, Okayama A, et al. A distinct role for Pin1 in the induction and maintenance of … in it what is gpo